06/10/2012 - Atualizado em 07/03/2013
The epidemiology of ALS and the role of population-based registries.
Ettore Beghi, Giancarlo Logroscino, Adriano Chiò, Orla Hardiman, Douglas Mitchell, Robert Swingler, Bryan J. Traynor on behalf of the EURALS Consortium.
Amyotrophic lateral sclerosis (ALS) is a degenerative disorder characterized by loss of upper and lower motor neurons, culminating in respiratory insufficiency and death after 3/5 years. The disease has several peculiarities: it is fairly rare, its natural history varies with age and sex, its etiology is unknown, it cannot be prevented, and there are few if any options for the treatment of the disease and its complications.